Categories
types of cancer

Osteosarcoma

Overview

Osteosarcoma, sometimes called osteogenic sarcoma. Though it is a rare disease, it is the most common kind of bone cancer which begins in cells that form bones. In very rare instances, it occurs in soft tissue outside the bone. Osteosarcoma is most often found in the long bones – more often the legs, but sometimes the arms – but it can start in any bone. It is mostly found in children and teens. It can affect adults, too, but teenage boys are most likely to get it. Osteosarcoma happens when the cells that grow new bone form a cancerous tumour. In children and teens, osteosarcoma often happens at the ends of long bones, where bone grows quickest. Often tumours develop around the knee, either in the lower part of the thighbone or the upper part of the shinbone. They may also grow in the upper arm bone close to the shoulder. However, osteosarcoma can develop in any bone in your body, especially in older adults. Treatment for osteosarcoma usually involves chemotherapy and surgery. Typically, radiation therapy is not effective in treating osteosarcoma, though the use of new improved radiation techniques, such as proton beam therapy, is being studied.

Symptoms

Symptoms for osteosarcoma include:

  • Swelling or lumps around bones or the ends of bones.
  • Bone or joint pain or soreness. This pain may come and go for months.
  • Broken bones that don’t seem to be caused by normal events like a fall.
  • The patient may have pain at night or after he/she plays or exercises. There may be a limp if the osteosarcoma affects the legs. Initially, the pain may not be very constant, but it tends to worsen overnight, usually increasing with activity. Telangiectatic osteosarcomas are a rare type of sarcoma that tends to weaken bones more than other forms of osteosarcomas. These are more likely to cause fractures at the location of the tumour.

    Causes

    The cause of osteosarcoma is not clear and most cases appear to occur sporadically. The condition seems to stem from an error in the child’s DNA, or genetic code. Bone-growing cells make osteosarcoma tumours by mistake. Teenagers who have a “growth spurt” are most likely to get it, and taller kids could have higher risks. A possible link between the speed of the growth spurt and the development of osteosarcoma is also being studied. Treatments like radiation therapy for other types of cancer, or cancer medicines called alkylating agents, can could put the patient at a higher risk of getting osteosarcoma. Certain illnesses, like Paget’s disease of the bone or a type of eye cancer called hereditary retinoblastoma, may also raise the risk. Some of the other risk factors are inherited genetic conditions such as Bloom syndrome, Li-Fraumeni syndrome, Rothmund-Thomson syndrome and Diamond-Blackfan anaemia.

    Diagnosis

    After taking the medical history and family health background the doctor may check the patient’s body for unusual lumps around bones, or to figure out what’s causing the pain. Imaging tests like X-rays, CT scans, MRIs, or bone scans may be recommended. These can show unusual changes in bones that may be signs of osteosarcoma. They can also show areas where the tumour may have spread. If there are signs of the disease on imaging tests, a biopsy maybe recommended. In a biopsy, a small sample of bone or tissue from a painful or swollen area is taken. The biopsy can show whether the tissue is cancerous and also reveals the cancer’s grade, which helps doctors understand how aggressive the cancer may be. Types of biopsy procedures used to diagnose osteosarcoma include:

  • Needle biopsy: The doctor inserts a thin needle through the skin and guides it into the tumour. The needle is used to remove small pieces of tissue from the tumour.
  • Surgical biopsy: The doctor makes an incision through the skin and removes either the entire tumour (excisional biopsy) or a portion of the tumour (incisional biopsy).
  • Treatment

    There are different kinds of treatment for osteosarcoma. The treatment for osteosarcoma depends on several things, such as the tumour’s location, how aggressive it is and whether it has spread. Age and overall health of the patient is also factored in. Most people with osteosarcoma need both surgery and chemotherapy. In some cases radiation therapy is also administered. Surgery: The goal of surgery is to remove the cancer cells, but surgeons also perform operations to maintain function and minimize disability. The extent of surgery for osteosarcoma depends on several factors, such as the tumour size, location and the person’s age. <

      li>Limb-sparing surgery: In most cases, surgery for osteosarcoma focuses on removing the tumour and sparing the limb so that function can be maintained. Its feasibility depends, in part, on the extent of the cancer and how much muscle and tissue need to be removed.
    • Amputation: With advancements in limb-sparing surgery, amputation has greatly reduced over the years. If amputation is necessary, advances in prosthetic joints can significantly improve outcomes and function.
    • Rotationplasty: In this surgery, sometimes used for children who are still growing, the surgeon removes the tumour and surrounding area, including the knee joint. The foot and ankle are then rotated and the ankle functions as a knee. A prosthesis is used for the lower leg and foot. Results typically enable the person to function very well in physical activities, sports and daily living.
    Chemotherapy: Doctors treat most osteosarcomas with chemotherapy. It helps in shrinking the tumour, which in turn makes surgery easier. It also gets rid of small clusters of cancer cells in the body that doctors may not be able to see on medical scans. Children tend to have less severe side effects from chemo than adults. Due to this, the doctor may use higher doses of chemo to try to kill the tumour. Some side effects may include nausea and vomiting, lack of hunger and diarrhoea. Radiation Therapy: Usually radiation is not used to treat osteosarcoma. However, the doctor may recommend this option in certain circumstances. During radiation therapy, doctors can use high-energy X-rays to kill cancer cells. It doesn’t work as well on osteosarcoma cells as it may with the cells of other cancers but the doctor might consider what’s called external beam radiation therapy if surgery can’t remove all the cancer. That often happens when the tumour is in the hip or jaw bone. This type of therapy focuses high-energy beams on the tumour from a machine outside the body to kill the remaining cancer cells.

    227 replies on “Osteosarcoma”

    Excellent post. I was checking constantly this blog and Iam impressed! Extremely helpful information particularlythe last part 🙂 I care for such info much. I was seeking this certain info for along time. Thank you and good luck.

    A fascinating discussion is definitely worth comment. I think that you need to publish more on this subject, it might not be a taboo matter but typically people don’t talk about such subjects. To the next! All the best!

    Hello There. I found your blog using msn.This is an extremely well written article. I will make sure to bookmark itand return to read more of your useful info. Thanks for thepost. I’ll certainly comeback.

    I do agree with all of the concepts you have offered to your post. They are really convincing and can certainly work. Nonetheless, the posts are very quick for novices. Could you please extend them a bit from next time? Thank you for the post.

    I have not checked in here for some time as I thought it was getting boring, but the last few posts are great quality so I guess I’ll add you back to my daily bloglist. You deserve it my friend 🙂

    Hey There. I found your blog using msn. This is an extremely well written article.I’ll make sure to bookmark it and come back to read more of your useful information. Thanks for the post.I’ll certainly comeback.

    whoah this blog is great i really like reading your posts.Keep up the good work! You realize, a lot of individuals are looking around for this information, you could help them greatly.my blog post – meteoritegarden.com

    Nice post. I was checking constantly this blog and I am impressed! Extremely useful info particularly the last part 🙂 I care for such information much. I was seeking this particular information for a long time. Thank you and good luck.

    I like the helpful info you supply on your articles.I’ll bookmark your blog and check again here frequently.I’m relatively sure I will learn lots of new stuff right here!Good luck for the next!

    Nice post. I was checking constantly this blog and I am impressed! Extremely useful info specifically the last part 🙂 I care for such information much. I was looking for this particular info for a very long time. Thank you and good luck.

    I will immediately take hold of your rss as I can’t find your e-mail subscription link or newsletter service. Do you have any? Please let me understand so that I may just subscribe. Thanks.

    I really wanted to compose a simple comment to be able to thank you for the pleasant tips and hints you are giving out on this site. My rather long internet look up has at the end been rewarded with awesome content to share with my friends and family. I ‘d believe that many of us visitors actually are unquestionably fortunate to live in a decent site with many lovely individuals with very beneficial methods. I feel very happy to have encountered your entire website page and look forward to so many more brilliant minutes reading here. Thank you once more for everything.

    I?¦m not sure where you are getting your information, however good topic. I must spend some time studying much more or working out more. Thanks for excellent information I used to be searching for this info for my mission.

    It as difficult to find well-informed people in this particular topic, but you seem like you know what you are talking about! Thanks

    Good day! Do you know if they make any plugins to help with Search Engine Optimization? I’m trying to get my blog to rank for some targeted keywords but I’m not seeing very good results. If you know of any please share. Thank you!

    I’m not sure where you’re getting your info, but goodtopic. I needs to spend some time learning more or understanding more.Thanks for excellent info I was looking for this info for my mission.

    Do you have a spam issue on this blog; I also am a blogger, and I was curious about your situation; many of us have created some nice methods and we are looking to exchange techniques with other folks, be sure to shoot me an email if interested.

    It’s an amazing paragraph designed for all the online viewers; they will takebenefit from it I am sure.

    Attractive section of content. I just stumbled upon your blog and in accession capital to assert that I get in fact enjoyed account your blog posts. Anyway I’ll be subscribing to your augment and even I achievement you access consistently quickly.

    Hi! I’m at work surfing around your blog from mynew iphone 3gs! Just wanted to say I love reading your blog and look forward toall your posts! Carry on the excellent work!

    Pretty nice post. I just stumbled upon your blog and wished to say thatI have truly enjoyed surfing around your blog posts.In any case I’ll be subscribing to your feed and I hope you write again soon!

    Wow! This could be one particular of the most beneficial blogs We ave ever arrive across on this subject. Actually Wonderful. I am also an expert in this topic so I can understand your effort.

    The safest cryptocurrency casinos make it convenient for players to utilize a variety of secure deposit and withdrawal methods. The best online casino sites featured here accept numerous cryptocurrencies, and most of them won’t turn fiat depositors away. 940-373-0803 To thank the men and women of our armed forces for their service, Desert Diamond Casino West Valley is giving our troops more with the Tribute Rewards Card: Patient Education Blackjack is probably the most recognized casino game in the world today. Multiple players can be involved at the same time, but it comes down to a 1-on-1 showdown between the player and the dealer. Between 8 to 12 decks of cards are being used and the goal is to beat the dealer by adding up your cards to 21. If you can do it in 2 cards, it means you managed to score a blackjack, which is the optimal card combination and will give you the biggest return. Your aim should be to get to 21 or as close to it as possible without going over. If you manage to do that better than the dealer, you will win. The race to 21 at the Blackjack table certainly provides plenty of thrills and spills. https://crossbowconsulting.co.ke/index.php/community/profile/bradyesf9836347/ Cadabrus casino tarjoaa tuoreen non sticky bonus tarjouksen. Tämä suomalaisten pelaajien käyttöön tarjottu bonus tuli tarjolle 13.10.2020. Saat uutena pelaajana 200% no-sticky bonuksen aina 100€ asti. Isommalle tallettajalle sopii parhaiten 100% avoin bonus 500€ asti, jonka päälle tarjotaan vielä 100 ilmaiskierrosta. Live casino pelaajalle parhaiten sopii cashback bonus, joka antaa sinulle rahat takaisin tappioista 10% suuruudella aina 200€ asti. Before deciding on which bonuses might be the best fit for you, it’s worth investigating a few common themes you’ll encounter when playing choosing a casino bonus. Firstly, investigating whether or not a bonus is ‘sticky’ or ‘non-sticky should be a major consideration when deciding on accepting a bonus. Other considerations should include the allowable wagering amounts, which games you are eligible to play with the bonus, and, if you’re playing slots, which type of slot best suits your needs.

    Right here is the perfect webpage for anybody who hopes to find out about this topic. You realize a whole lot its almost hard to argue with you (not that I really will need to…HaHa). You definitely put a brand new spin on a topic that has been discussed for years. Excellent stuff, just wonderful.

    Hi there, just became aware of your blog through Google, andfound that it is truly informative. I’m gonna watch outfor brussels. I will appreciate if you continue this in future.Numerous people will be benefited from your writing.Cheers!

    Campobet è un bookmaker internazionale al quale è possibile anche giocare dall’italia, pur non possedendo la licenza AAMS.

    I want to to thank you for this wonderful read!! I definitely enjoyed every little bit of it. I have you bookmarked to check out new stuff you postÖ

    Having an interior designer is incredibly important since they have the knowledge and experience to help transform a space into something functional and aesthetically pleasing. Interior designers know how to balance colour, texture, furniture, and other design elements to create the desired look. They are creative problem solvers and can work their magic in any space from small closets to large outdoor decks. With an expert’s eye for detail, your own ideas can be refined and executed perfectly, elevating your space both functionally and aesthetically. Thank you for providing this content and helping us recognize the importance of hiring an interior designer!

    Hello There. I discovered your blog the usageof msn. This is an extremely neatly written article.I’ll make sure to bookmark it and return to read moreof your helpful information. Thanks for the post.I will definitely comeback.

    [url=https://over-the-counter-drug.com/#]is zofran over the counter[/url] over the counter diuretic

    Hey There. I found your blog using msn. This is an extremely well written article. I will make sure to bookmark it and return to read more of your useful information. Thanks for the post. I’ll certainly return.

    ซื้อของผ่านEbayแล้วTrackingไม่อัพเดตมาเป็นอาทิตย์แล้วครับ ผมได้สั่งของจากEbayไปวันที่ 31 กรกฎาคม ส่งโดยUSPS แบบFirst Class Package International Service ครับ ซื้อของ

    A fascinating discussion is definitely worth comment. I believe that you need to publish more about this subject matter, it might not be a taboo subject but typically people do not talk about such subjects. To the next! Kind regards!

    Hey There. I found your blog the usage of msn. That is avery well written article. I will be sure to bookmark it and come back to learn extra of your helpful information. Thank you for the post.I will definitely comeback.

    Excellent post. I was checking continuously this blog and I’m impressed!Extremely helpful information specially the last part🙂 I care for such info a lot. I was looking for this certain info for a very long time.Thank you and good luck.

    Hello! I could have sworn I’ve visited this site before but after looking at some of the articles I realized it’s new to me. Nonetheless, I’m certainly happy I came across it and I’ll be book-marking it and checking back regularly.

    Thanks for the marvelous posting! I really enjoyed reading it, you might be a greatauthor. I will be sure to bookmark your blog and will often come back down the road.I want to encourage you to continue your great writing, have a nice evening!

    An interesting discussion is worth comment. I do think that you need to write more on this subject, it might not be a taboo subject but usually people don’t discuss such issues. To the next! Kind regards!

    Nice post. I learn something new and challenging on blogs I stumbleupon on a daily basis. It’s always interesting to read through content from other writers and practice a little something from other sites.

    An intriguing discussion is definitely worth comment. There’s no doubt that that you should publish more on this subject, it may not be a taboo matter but usually people do not talk about these subjects. To the next! Kind regards!!

    After checking out a number of the articles on your site, I truly like your technique of writing a blog. I added it to my bookmark site list and will be checking back soon. Please visit my website as well and tell me what you think.

    Leave a Reply

    Your email address will not be published. Required fields are marked *